Publicacions (130) Publicacions de Jose Ruiz Lopez

2024

  1. Novel 2-(5-Arylthiophen-2-yl)-benzoazole Cyclometalated Iridium(III) dppz Complexes Exhibit Selective Phototoxicity in Cancer Cells by Lysosomal Damage and Oncosis

    Journal of Medicinal Chemistry, Vol. 67, Núm. 1, pp. 691-708

  2. Photoactivatable Ruthenium Complexes Containing Minimal Straining Benzothiazolyl-1,2,3-triazole Chelators for Cancer Treatment

    Inorganic Chemistry, Vol. 63, Núm. 14, pp. 6202-6216

  3. Photoactivatable, mitochondria targeting dppz iridium(III) complex selectively interacts and damages mitochondrial DNA in cancer cells

    Chemico-Biological Interactions, Vol. 392

2023

  1. A near-infrared light-activatable Ru(ii)-coumarin photosensitizer active under hypoxic conditions

    Chemical Science, Vol. 14, Núm. 26, pp. 7170-7184

  2. Cyclometalated Benzimidazole Osmium(II) Complexes with Antiproliferative Activity in Cancer Cells Disrupt Calcium Homeostasis

    Inorganic Chemistry, Vol. 62, Núm. 16, pp. 6474-6487

  3. Exploring Structure-Activity Relationships in Photodynamic Therapy Anticancer Agents Based on Ir(III)-COUPY Conjugates

    Journal of Medicinal Chemistry, Vol. 66, Núm. 12, pp. 7849-7867

  4. Ir(III) Compounds Containing a Terdentate Ligand Are Potent Inhibitors of Proliferation and Effective Antimetastatic Agents in Aggressive Triple-Negative Breast Cancer Cells

    Journal of Medicinal Chemistry, Vol. 66, Núm. 14, pp. 9766-9783

  5. Newly synthesized benzothiazolyl-1,2,3-triazole derivatives: Intramolecular charge transfer tuning, solvatofluorochromism and antiproliferative properties

    Dyes and Pigments, Vol. 209

  6. Novel valproate half-sandwich rhodium and iridium conjugates to fight against multidrug-resistant Gram-positive bacteria

    Dalton Transactions, Vol. 52, Núm. 38, pp. 13482-13486

2022

  1. Dipyridophenazine iridium(III) complex as a phototoxic cancer stem cell selective, mitochondria targeting agent

    Chemico-Biological Interactions, Vol. 360

  2. Improving Photodynamic Therapy Anticancer Activity of a Mitochondria-Targeted Coumarin Photosensitizer Using a Polyurethane-Polyurea Hybrid Nanocarrier

    Biomacromolecules, Vol. 23, Núm. 7, pp. 2900-2913

  3. Inert cationic iridium(iii) complexes with phenanthroline-based ligands: application in antimicrobial inactivation of multidrug-resistant bacterial strains

    Dalton Transactions, Vol. 51, Núm. 25, pp. 9653-9663

  4. Polyurethane-polyurea hybrid nanocapsules as efficient delivery systems of anticancer Ir(iii) metallodrugs

    Inorganic Chemistry Frontiers

  5. Potent anticancer activity of a novel iridium metallodrug via oncosis

    Cellular and Molecular Life Sciences, Vol. 79, Núm. 10

2021

  1. A 2-(benzothiazol-2-yl)-phenolato platinum(II) complex as potential photosensitizer for combating bacterial infections in lung cancer chemotherapy†

    European Journal of Medicinal Chemistry, Vol. 222

  2. A Cyclometalated IrIII Complex Conjugated to a Coumarin Derivative Is a Potent Photodynamic Agent against Prostate Differentiated and Tumorigenic Cancer Stem Cells

    Chemistry - A European Journal, Vol. 27, Núm. 33, pp. 8547-8556

  3. A photoactivated Ir(iii) complex targets cancer stem cells and induces secretion of damage-associated molecular patterns in melanoma cells characteristic of immunogenic cell death

    Inorganic Chemistry Frontiers, Vol. 8, Núm. 21, pp. 4696-4711

  4. COUPY Coumarins as Novel Mitochondria-Targeted Photodynamic Therapy Anticancer Agents

    Journal of Medicinal Chemistry, Vol. 64, Núm. 23, pp. 17209-17220

  5. Novel organo-osmium(ii) proteosynthesis inhibitors active against human ovarian cancer cells reduce gonad tumor growth in: Caenorhabditis elegans

    Inorganic Chemistry Frontiers, Vol. 8, Núm. 1, pp. 141-155

  6. Organoplatinum(II) Complexes Self-Assemble and Recognize AT-Rich Duplex DNA Sequences

    Inorganic Chemistry, Vol. 60, Núm. 4, pp. 2178-2187