Publicaciones (131) Publicaciones de Jose Ruiz Lopez

2024

  1. Novel 2-(5-Arylthiophen-2-yl)-benzoazole Cyclometalated Iridium(III) dppz Complexes Exhibit Selective Phototoxicity in Cancer Cells by Lysosomal Damage and Oncosis

    Journal of Medicinal Chemistry, Vol. 67, Núm. 1, pp. 691-708

  2. Photoactivatable Ruthenium Complexes Containing Minimal Straining Benzothiazolyl-1,2,3-triazole Chelators for Cancer Treatment

    Inorganic Chemistry, Vol. 63, Núm. 14, pp. 6202-6216

  3. Photoactivatable, mitochondria targeting dppz iridium(III) complex selectively interacts and damages mitochondrial DNA in cancer cells

    Chemico-Biological Interactions, Vol. 392

2023

  1. A near-infrared light-activatable Ru(ii)-coumarin photosensitizer active under hypoxic conditions

    Chemical Science, Vol. 14, Núm. 26, pp. 7170-7184

  2. Cyclometalated Benzimidazole Osmium(II) Complexes with Antiproliferative Activity in Cancer Cells Disrupt Calcium Homeostasis

    Inorganic Chemistry, Vol. 62, Núm. 16, pp. 6474-6487

  3. Exploring Structure-Activity Relationships in Photodynamic Therapy Anticancer Agents Based on Ir(III)-COUPY Conjugates

    Journal of Medicinal Chemistry, Vol. 66, Núm. 12, pp. 7849-7867

  4. Ir(III) Compounds Containing a Terdentate Ligand Are Potent Inhibitors of Proliferation and Effective Antimetastatic Agents in Aggressive Triple-Negative Breast Cancer Cells

    Journal of Medicinal Chemistry, Vol. 66, Núm. 14, pp. 9766-9783

  5. Newly synthesized benzothiazolyl-1,2,3-triazole derivatives: Intramolecular charge transfer tuning, solvatofluorochromism and antiproliferative properties

    Dyes and Pigments, Vol. 209

  6. Novel Re(I) Complexes as Potential Selective Theranostic Agents in Cancer Cells and In Vivo in Caenorhabditis elegans Tumoral Strains

    Journal of Medicinal Chemistry

  7. Novel valproate half-sandwich rhodium and iridium conjugates to fight against multidrug-resistant Gram-positive bacteria

    Dalton Transactions, Vol. 52, Núm. 38, pp. 13482-13486

2022

  1. Dipyridophenazine iridium(III) complex as a phototoxic cancer stem cell selective, mitochondria targeting agent

    Chemico-Biological Interactions, Vol. 360

  2. Improving Photodynamic Therapy Anticancer Activity of a Mitochondria-Targeted Coumarin Photosensitizer Using a Polyurethane-Polyurea Hybrid Nanocarrier

    Biomacromolecules, Vol. 23, Núm. 7, pp. 2900-2913

  3. Inert cationic iridium(iii) complexes with phenanthroline-based ligands: application in antimicrobial inactivation of multidrug-resistant bacterial strains

    Dalton Transactions, Vol. 51, Núm. 25, pp. 9653-9663

  4. Polyurethane-polyurea hybrid nanocapsules as efficient delivery systems of anticancer Ir(iii) metallodrugs

    Inorganic Chemistry Frontiers

  5. Potent anticancer activity of a novel iridium metallodrug via oncosis

    Cellular and Molecular Life Sciences, Vol. 79, Núm. 10

2021

  1. A 2-(benzothiazol-2-yl)-phenolato platinum(II) complex as potential photosensitizer for combating bacterial infections in lung cancer chemotherapy†

    European Journal of Medicinal Chemistry, Vol. 222

  2. A Cyclometalated IrIII Complex Conjugated to a Coumarin Derivative Is a Potent Photodynamic Agent against Prostate Differentiated and Tumorigenic Cancer Stem Cells

    Chemistry - A European Journal, Vol. 27, Núm. 33, pp. 8547-8556

  3. A photoactivated Ir(iii) complex targets cancer stem cells and induces secretion of damage-associated molecular patterns in melanoma cells characteristic of immunogenic cell death

    Inorganic Chemistry Frontiers, Vol. 8, Núm. 21, pp. 4696-4711

  4. COUPY Coumarins as Novel Mitochondria-Targeted Photodynamic Therapy Anticancer Agents

    Journal of Medicinal Chemistry, Vol. 64, Núm. 23, pp. 17209-17220

  5. Novel organo-osmium(ii) proteosynthesis inhibitors active against human ovarian cancer cells reduce gonad tumor growth in: Caenorhabditis elegans

    Inorganic Chemistry Frontiers, Vol. 8, Núm. 1, pp. 141-155