Publications (23) Publications de Francisco Jose Roca Soler

2023

  1. Gaucher disease protects against tuberculosis

    Proceedings of the National Academy of Sciences of the United States of America, Vol. 120, Núm. 7

2022

  1. Tumor necrosis factor induces pathogenic mitochondrial ROS in tuberculosis through reverse electron transport

    Science, Vol. 376, Núm. 6600

2021

  1. Elevated cerebrospinal fluid cytokine levels in tuberculous meningitis predict survival in response to dexamethasone

    Proceedings of the National Academy of Sciences of the United States of America, Vol. 118, Núm. 10

  2. Erratum: Elevated cerebrospinal fluid cytokine levels in tuberculous meningitis predict survival in response to dexamethasone (Proc. Natl. Acad. Sci. U.S.A. (2021) 118 (e2024852118) DOI: 10.1073/pnas.2024852118)

    Proceedings of the National Academy of Sciences of the United States of America

  3. Tumor necrosis factor and schistosoma mansoni egg antigen omega-1 shape distinct aspects of the early egg-induced granulomatous response

    PLoS Neglected Tropical Diseases, Vol. 15, Núm. 1, pp. 1-12

2019

  1. TNF Induces Pathogenic Programmed Macrophage Necrosis in Tuberculosis through a Mitochondrial-Lysosomal-Endoplasmic Reticulum Circuit

    Cell, Vol. 178, Núm. 6, pp. 1344-1361.e11

2016

  1. TNFα Impairs Rhabdoviral Clearance by Inhibiting the Host Autophagic Antiviral Response

    PLoS Pathogens, Vol. 12, Núm. 6

2015

  1. Adventures within the speckled band: Heterogeneity, angiogenesis, and balanced inflammation in the tuberculous granuloma

    Immunological Reviews, Vol. 264, Núm. 1, pp. 276-287

2013

  1. An Enzyme That Inactivates the Inflammatory Mediator Leukotriene B4 Restricts Mycobacterial Infection

    PLoS ONE, Vol. 8, Núm. 7

  2. TNF dually mediates resistance and susceptibility to mycobacteria via mitochondrial reactive oxygen species

    Cell, Vol. 153, Núm. 3, pp. 521-534

  3. TNF receptors regulate vascular homeostasis in zebrafish through a caspase-8, caspase-2 and P53 apoptotic program that bypasses caspase-3

    DMM Disease Models and Mechanisms, Vol. 6, Núm. 2, pp. 383-396

2012

  1. Host genotype-specific therapies can optimize the inflammatory response to mycobacterial infections

    Cell, Vol. 148, Núm. 3, pp. 434-446

2011

  1. Evolutionary conserved pro-inflammatory and antigen presentation functions of zebrafish IFNγ revealed by transcriptomic and functional analysis

    Molecular Immunology, Vol. 48, Núm. 9-10, pp. 1073-1083

2010

  1. Molecular strategies used by fish pathogens to interfere with host-programmed cell death

    Developmental and Comparative Immunology, Vol. 34, Núm. 6, pp. 603-610

  2. Zebrafish larvae are unable to mount a protective antiviral response against waterborne infection by spring viremia of carp virus

    Developmental and Comparative Immunology, Vol. 34, Núm. 5, pp. 546-552

2009

  1. Evolution of lipopolysaccharide (LPS) recognition and signaling: Fish TLR4 does not recognize LPS and negatively regulates NF-κB activation

    Journal of Immunology, Vol. 182, Núm. 4, pp. 1836-1845

  2. New insights into the evolution of IFNs: Zebrafish group II IFNs induce a rapid and transient expression of IFN-dependent genes and display powerful antiviral activities

    Journal of Immunology, Vol. 182, Núm. 6, pp. 3440-3449

2008

  1. Characterization of macrophages from the bony fish gilthead seabream using an antibody against the macrophage colony-stimulating factor receptor

    Developmental and Comparative Immunology, Vol. 32, Núm. 10, pp. 1151-1159

  2. Evolution of the inflammatory response in vertebrates: Fish TNF-α is a powerful activator of endothelial cells but hardly activates phagocytes

    Journal of Immunology, Vol. 181, Núm. 7, pp. 5071-5081

2007

  1. Post-transcriptional regulation of cytokine genes in fish: A role for conserved AU-rich elements located in the 3′-untranslated region of their mRNAs

    Molecular Immunology, Vol. 44, Núm. 4, pp. 472-478