Jose Neptuno
Rodriguez Lopez
Catedraticos de Universidad
Hospital Virgen de la Arrixaca
Murcia, EspañaPublications in collaboration with researchers from Hospital Virgen de la Arrixaca (31)
2023
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Targeting protein methylation in pancreatic cancer cells results in KRAS signaling imbalance and inhibition of autophagy
Cell Death and Disease, Vol. 14, Núm. 11
2021
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Acriflavine, a potent inhibitor of HIF-1α, disturbs glucose metabolism and suppresses ATF4-protective pathways in melanoma under non-hypoxic conditions
Cancers, Vol. 13, Núm. 1, pp. 1-17
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MITF induces escape from innate immunity in melanoma
Journal of Experimental and Clinical Cancer Research, Vol. 40, Núm. 1
2020
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PRMT1-dependent methylation of BRCA1 contributes to the epigenetic defense of breast cancer cells against ionizing radiation
Scientific Reports, Vol. 10, Núm. 1
2019
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Mitotic rate as an important prognostic factor in cutaneous malignant melanoma
Clinical and Translational Oncology, Vol. 21, Núm. 10, pp. 1348-1356
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Prognostic value of the Breslow:diameter ratio in cutaneous melanoma
Journal of the American Academy of Dermatology, Vol. 80, Núm. 3, pp. 806-808
2016
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Targeting the epigenetics of the DNA damage response in breast cancer
Cell Death and Disease, Vol. 7
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Tumor suppressor SET9 guides the epigenetic plasticity of breast cancer cells and serves as an early-stage biomarker for predicting metastasis
Oncogene, Vol. 35, Núm. 47, pp. 6143-6152
2015
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Dysregulated cholinergic network as a novel biomarker of poor prognostic in patients with head and neck squamous cell carcinoma
BMC Cancer, Vol. 15, Núm. 1
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Targeting the epigenetic machinery of cancer cells
Oncogene, Vol. 34, Núm. 2, pp. 135-143
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Unbalanced acetylcholinesterase activity in larynx squamous cell carcinoma
International Immunopharmacology, Vol. 29, Núm. 1, pp. 81-86
2013
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Directed Phenotype Switching as an Effective Antimelanoma Strategy
Cancer Cell, Vol. 24, Núm. 1, pp. 105-119
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Suppression of antifolate resistance by targeting the myosin Va trafficking pathway in melanoma
Neoplasia (United States), Vol. 15, Núm. 7, pp. 826-839
2012
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Melanoma coordinates general and cell-specific mechanisms to promote methotrexate resistance
Experimental Cell Research, Vol. 318, Núm. 10, pp. 1146-1159
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Reactivation of the Tumour Suppressor RASSF1A in Breast Cancer by Simultaneous Targeting of DNA and E2F1 Methylation
PLoS ONE, Vol. 7, Núm. 12
2010
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Analysis of cholinesterases in human prostate and sperm. Implications in cancer and fertility
Chemico-Biological Interactions, Vol. 187, Núm. 1-3, pp. 432-435
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Mechanism of dihydrofolate reductase downregulation in melanoma by 3-O-(3,4,5-trimethoxybenzoyl)-(-)-epicatechin
Journal of Cellular Biochemistry, Vol. 110, Núm. 6, pp. 1399-1409
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Purification and kinetic properties of human recombinant dihydrofolate reductase produced in bombyx mori chrysalides
Applied Biochemistry and Biotechnology, Vol. 162, Núm. 7, pp. 1834-1846
2009
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Binding of natural and synthetic polyphenols to human dihydrofolate reductase
International Journal of Molecular Sciences, Vol. 10, Núm. 12, pp. 5398-5410
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Melanoma activation of 3-O-(3,4,5-trimethoxybenzoyl)-(-)-epicatechin to a potent irreversible inhibitor of dihydrofolate reductase
Molecular Pharmaceutics, Vol. 6, Núm. 3, pp. 883-894