Phytomelatonin content in Valeriana officinalis L. and some related phytotherapeutic supplements

  1. Losada, Marta
  2. Cano, Antonio
  3. Hernández-Ruiz, Josefa
  4. Arnao, Marino B.
Journal:
International Journal of Plant Based Pharmaceuticals

ISSN: 2791-7509

Year of publication: 2022

Volume: 2

Issue: 2

Pages: 176-181

Type: Article

DOI: 10.55484/IJPBP.1079005 GOOGLE SCHOLAR lock_openOpen access editor

More publications in: International Journal of Plant Based Pharmaceuticals

Bibliographic References

  • Arnao, M.B., 2014. Phytomelatonin: discovery, content, and role in plants. Advances in Botany, e815769.
  • Arnao, M.B., Hernández‐Ruiz, J., 2009. Assessment of different sample processing procedures applied to the determination of melatonin in plants. Phytochemical Analysis, 20(1), 14-18.
  • Arnao, M.B., Hernández-Ruiz, J., 2013. Growth conditions influence the melatonin content of tomato plants. Food Chemistry, 138(2-3), 1212-1214.
  • Arnao, M.B., Hernández-Ruiz, J., 2014. Melatonin: plant growth regulator and/or biostimulator during stress?. Trends in Plant Science, 19(12), 789-797.
  • Arnao, M.B., Hernández-Ruiz, J., 2015. Phytomelatonin: Searching for plants with high levels as a natural source of nutraceuticals. In F. R. S. Atta-Ür-Rahman (Ed.), Studies in Natural Products Chemistry (Bioactive Natural Products) vol. 46 (Vol. 1–11, pp. 519–545). Elsevier Science Publishers.
  • Arnao, M.B., Hernández-Ruiz, J., 2018. The potential of phytomelatonin as a nutraceutical. Molecules, 23(1), 238.
  • Bartolucci, S., Mari, M., Di Gregorio, G., Piersanti, G., 2016. Observations concerning the synthesis of tryptamine homologues and branched tryptamine derivatives via the borrowing hydrogen process: synthesis of psilocin, bufotenin, and serotonin. Tetrahedron, 72(18), 2233-2238.
  • Barton, D.L., Atherton, P.J., Bauer, B.A., Moore Jr, D.F., Mattar, B.I., LaVasseur, B.I., Loprinzi, C.L., 2011. The use of Valeriana officinalis (valerian) in improving sleep in patients who are undergoing treatment for cancer: A phase III randomized, placebo-controlled, double-blind study: NCCTG Trial, N01C5. The Journal of Supportive Oncology, 9(1), 24-31.
  • Bent, S., Padula, A., Moore, D., Patterson, M., Mehling, W., 2006. Valerian for sleep: a systematic review and meta-analysis. The American Journal of Medicine, 119(12), 1005-1012.
  • Boonstra, E., De Kleijn, R., Colzato, L.S., Alkemade, A., Forstmann, B.U., Nieuwenhuis, S., 2015. Neurotransmitters as food supplements: the effects of GABA on brain and behavior. Frontiers in Psychology, 6, 1520.
  • Borrás, S., Martínez-Solís, I., Ríos, J.L., 2021. Medicinal Plants for Insomnia Related to Anxiety: An Updated Review. Planta Medica, 87, 738–753.
  • Cheng, G., Ma, T., Deng, Z., Gutiérrez-Gamboa, G., Ge, Q., Xu, P., Sun, X., 2021. Plant-derived melatonin from food: A gift of nature. Food & Function, 12(7), 2829-2849.
  • Coppens, P., Da Silva, M.F., Pettman, S., 2006. European regulations on nutraceuticals, dietary supplements and functional foods: a framework based on safety. Toxicology, 221(1), 59-74.
  • Dahlitz, M., Alvarez, B., Parkes, J.D., English, J., Arendt, J., Vignau, J., 1991. Delayed sleep phase syndrome response to melatonin. The Lancet, 337(8750), 1121-1124.
  • Das, G., Shin, H.S., Tundis, R., Gonçalves, S., Tantengco, O.A.G., Campos, M.G., Patra, J.K., 2021. Plant Species of Sub-Family Valerianaceae—A Review on Its Effect on the Central Nervous System. Plants, 10(5), 846.
  • Dimpfel, W., Suter, A., 2008. Sleep improving effects of a single dose administration of a valerian/hops fluid extract—A double blind, randomized, placebo-controlled sleep-EEG study in a parallel design using electrohypnograms. European Journal of Medical Research, 13(5), 200–204.
  • EMA-HMP, 2018, September 17. Herbal medicinal products . European Medicines Agency. https://www.ema.europa.eu/en/human-regulatory/herbal-medicinal-products
  • Ferracioli-Oda, E., Qawasmi, A., Bloch, M.H., 2013. Meta-analysis: melatonin for the treatment of primary sleep disorders. PloS One, 8(5), e63773.
  • Finley, J.W., Finley, J.W., Ellwood, K., Hoadley, J., 2014. Launching a new food product or dietary supplement in the United States: industrial, regulatory, and nutritional considerations. Annual Review of Nutrition, 34, 421-447.
  • Hadley, S.K., Petry, J.J., 2003. Valerian. American Family Physician, 67(8), 1755-1758.
  • He, L., Li, J.L., Zhang, J.J., Su, P., Zheng, S.L., 2003. Microwave assisted synthesis of melatonin. Synthetic Communications, 33(5), 741-747.
  • Hernández-Ruiz, J., Arnao, M.B., 2008. Distribution of melatonin in different zones of lupin and barley plants at different ages in the presence and absence of light. Journal of Agricultural and Food Chemistry, 56(22), 10567-10573.
  • Herxheimer, A., 2005. Jet lag. Clinical Evidence, (13), 2178-2183.
  • HMPC-EMA, 2016. European Union herbal monograph on Valeriana officinalis L., radix. Herbal Medicinal Products Committee, EMA/HMPC/150848/2015, 9.
  • Jan, J.E., Hamilton, D., Seward, N., Fast, D.K., Freeman, R.D., Laudon, M., 2000. Clinical trials of controlled‐release melatonin in children with sleep–wake cycle disorders. Journal of Pineal Research, 29(1), 34-39.
  • Kennedy, D.A., Lupattelli, A., Koren, G., Nordeng, H., 2013. Herbal medicine use in pregnancy: results of a multinational study. BMC Complementary and Alternative Medicine, 13(1), 355.
  • Kim, Y.I., Lee, H., Nirmala, F.S., Seo, H.D., Ha, T.Y., Jung, C.H., Ahn, J., 2022. Antioxidant Activity of Valeriana fauriei Protects against Dexamethasone-Induced Muscle Atrophy. Oxidative Medicine and Cellular Longevity, 2022, 3645431.
  • Marde, V.S., Atkare, U.A., Gawali, S.V., Tiwari, P.L., Badole, S.P., Wankhede, N.L., Kale, M.B., 2022. Alzheimer’s disease and sleep disorders: Insights into the possible disease connections and the potential therapeutic targets. Asian Journal of Psychiatry, 68, 102961.
  • Matura, J.M., Shea, L.A., Bankes, V.A., 2021. Dietary supplements, cytochrome metabolism, and pharmacogenetic considerations. Irish Journal of Medical Science, 1971, 1-9.
  • Mayeno, A.N., Gleich, G.J., 1994, July. The eosinophilia-myalgia syndrome: lessons from Germany. In Mayo Clinic Proceedings (Vol. 69, No. 7, pp. 702-704). Elsevier.
  • Miyasaka, L.S., Atallah, Á.N., Soares, B., 2006. Valerian for anxiety disorders. Cochrane Database of Systematic Reviews, (4), CD004515.
  • Naylor, S., Johnson, K.L., Williamson, B.L., Klarskov, K., Gleich, G.J., 1999. Structural characterization of contaminants in commercial preparations of melatonin by on-line HPLC-electrospray ionization-tandem mass spectrometry. Advances in Experimental Medicine and Biology, 467, 769–777.
  • Palmieri, G., Contaldi, P., Fogliame, G., 2017. Evaluation of effectiveness and safety of a herbal compound in primary insomnia symptoms and sleep disturbances not related to medical or psychiatric causes. Nature and Science of Sleep, 9, 163-169.
  • Pérez-Llamas, F., Hernández-Ruiz, J., Cuesta, A., Zamora, S., Arnao, M.B., 2020. Development of a phytomelatonin-rich extract from cultured plants with excellent biochemical and functional properties as an alternative to synthetic melatonin. Antioxidants, 9(2), 158.
  • Rowe, S.B., 1999. What is a Nutrient? Defining the Food-Drug Continuum. In Round table forum, moderator’s comments. Georgetown University.
  • Shinjyo, N., Waddell, G., Green, J., 2020. Valerian root in treating sleep problems and associated disorders-A systematic review and meta-analysis. Journal of Evidence-Based Integrative Medicine, 25, 2515690X20967323.
  • Singh, B., Sharma, R.A., 2020. Secondary Metabolites of Medicinal Plants, 4 Volume Set: Ethnopharmacological Properties, Biological Activity and Production Strategies (1st ed.). Wiley-VCH.
  • Soltani, A., Bahrami, F., Bahari, Z., Shankayi, Z., Graily-Afra, M., Sahraei, H., 2021. The effects of Valerian on sleep spindles in a model of neuropathic pain. Sleep Science, 14(Spec 2), 133-139.
  • Spiess, D., Winker, M., Chauveau, A., Abegg, V.F., Potterat, O., Hamburger, M., Simões-Wüst, A.P., 2021. Medicinal Plants for the Treatment of Mental Diseases in Pregnancy: An In Vitro Safety Assessment. Planta Medica.
  • Taavoni, S., Ekbatani, N., Kashaniyan, M., Haghani, H., 2011. Effect of valerian on sleep quality in postmenopausal women: a randomized placebo-controlled clinical trial. Menopause, 18(9), 951-955.
  • Tammadon, M.R., Nobahar, M., Hydarinia-Naieni, Z., Ebrahimian, A., Ghorbani, R., Vafaei, A.A., 2021. The effects of valerian on sleep quality, depression, and state anxiety in hemodialysis patients: a randomized, double-blind, crossover clinical trial. Oman Medical Journal, 36(2), e255.
  • Thomson, D.W., Commeureuc, A.G., Berlin, S., Murphy, J.A., 2003. Efficient route to the pineal hormone melatonin by radical-based indole synthesis. Synthetic Communications, 33(20), 3631-3641.
  • Trauner, G., Khom, S., Baburin, I., Benedek, B., Hering, S., Kopp, B., 2008. Modulation of GABAA receptors by valerian extracts is related to the content of valerenic acid. Planta Medica, 74(1), 19-24.
  • Vanaclocha, B., Cañigueral Folcara, S., 2019. Fitoterapia. Vademécum de prescripción (5th ed.). Elsevier Science Publishers. https://tienda.elsevier.es/fitoterapia-vademecum-de-prescripcion-9788491132998.html
  • Wheatley, D., 2005. Medicinal plants for insomnia: a review of their pharmacology, efficacy and tolerability. Journal of Psychopharmacology, 19(4), 414-421.
  • Williamson, B.L., Tomlinson, A.J., Mishra, P.K., Gleich, G.J., Naylor, S., 1998. Structural characterization of contaminants found in commercial preparations of melatonin: similarities to case-related compounds from L-tryptophan associated with eosinophilia-myalgia syndrome. Chemical Research in Toxicology, 11(3), 234-240.
  • Xie, Z., Chen, F., Li, W.A., Geng, X., Li, C., Meng, X., Yu, F., 2017. A review of sleep disorders and melatonin. Neurological Research, 39(6), 559-565.