Humoral immune response in lambs and goat kids inoculated with a dual vaccine against contagious agalactia
- Fe Rodríguez, David Christian de la
- Rodríguez, Raúl
- Assunçao, Patricia Clemente Janeiro
- Ramírez, Ana
- Flores Mengual, María Pastora
- Poveda Guerrero, José B.
ISSN: 0213-5434, 1989-1784
Any de publicació: 2006
Número: 22
Pàgines: 87-91
Tipus: Article
Altres publicacions en: Anales de veterinaria de Murcia
Resum
A combined vaccine against Mycoplasma agalactiae and Mycoplasma mycoides subsp. mycoides (large colony type) was developed using inactivated strains selected in previous characterization studies. Phenol was used as inactivating agent and aluminium hydroxide was added as adjuvant. The present study was designed to evaluate the specific humoral immune response to these two mycoplasma species shown by lambs and goat kids. One group of 15 Pelibuey lambs and one group of 8 Canary goat kids received two injections of vaccine at the ages 45 and 70 days and were monitored until they were 120 days old. Antibody titres were determined by indirect ELISA. Lambs showed lower antibody levels (expressed as ODs) to both antigens than goat kids althought significantly differences were only registered to M. agalactiae antigen (P<0.005).