Inhibición de acetilcolinesterasa en conejos tras exposición subcrónica a metilparatióncomparación de los métodos de Ellman y de Voss y Sachsse

1. Ceron Madrigal, J.J.
2. Fernandez Del Palacio, M.J.
3. Bernal Gambin, L.
4. Gutierrez Panizo, C.

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Abstract

A significant inhibition of plasma acetylcholinesterase after 21 days of repeated ingestion of methylparathion at a dose rate of 1.73 mg/kg body weight was detected. This inhibition was also observed in whole blood with the Voss and Sachsse method. Ellman method did not have a correct reproducibility in whole blood.

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