Las transiciones en el uso de alcohol en una cohorte de nacimiento-sexo en la población general: el proyecto transversal PEGASUS-Murcia

  1. Mathilde M. Husky
  2. Chrianna Bhara
  3. Gemma Vilagut
  4. Diego Salmerón
  5. Salvador Martínez
  6. Carmen Navarro
  7. Jordi Alonso
  8. Ronald C. Kessler
  9. Fernando Navarro-Mateu
Journal:
Adicciones: Revista de socidrogalcohol

ISSN: 0214-4840

Year of publication: 2020

Volume: 32

Issue: 2

Pages: 94-104

Type: Article

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More publications in: Adicciones: Revista de socidrogalcohol

Abstract

To examine the potential impact of prevalence of alcohol use in a birth-sex cohort on subsequent initiation and progression of alcohol use in the PEGASUS-Murcia project, a cross-sectional survey of a representative sample of non-institutionalized adults in Murcia (Spain). Data on lifetime history of alcohol use, DSM-IV use disorders, and remission were collected from 1,459 adults using faceto-face interviewers based on the Composite International Diagnostic Interview (CIDI 3.0). Life-table estimates based on survival functions for alcohol use age-of-onset and remission were used as time-varying predictors of subsequent individual-level alcohol use in discrete-time survival models. Nearly nine out of ten adults had a lifetime alcohol use history at time of interview. Of these lifetime users, 84.3% became regular users (>12 drinks a year) and 5.5-1.6% went on to meet criteria for DSM-IV alcohol abuse or dependence, respectively. By the age of 18, 70.9% of respondents had used alcohol, and one half (50.2%) had used regularly. Regular use sharply increased during early adulthood to reach 90.8% by age 22. Birth-sex cohort alcohol use was significantly and positively associated with increased odds of all subsequent transitions examined except for the transition from use to abuse. The findings highlight sensitive periods with rapid transitions to higher levels of alcohol use and emphasize the importance of cohort experiences in the full spectrum of stages of alcohol use. These results may contribute to predicting population-levels trends in alcohol-related problems in Spain

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Funding information

The authors wish to thank all participants for their collaboration, the ?Observatorio sobre Drogas de la Regi?n de Murcia? and acknowledge to Carlos Giribert Mu?oz for his support in developing the PEGASUS-Murcia project when he was the Deputy Director of Programs, Chronicity and Innovation of the Health Authority of Murcia. The PEGASUS-Murcia Project was supported by the Regional Health Authorities of Murcia (?Servicio Murciano de Salud and Consejer?a de Sanidad y Pol?tica Social?) (Decreto n? 455/2009) and the ?Fundaci?n para la Formaci?n e Investigaci?n Sanitarias (FFIS) de la Regi?n de Murcia? (N? Expedientes: CM0829 I and FFIDS/ EMER09/14). The PEGASUS-Murcia project is carried out in conjunction with the WHOWMH Survey Initiative. C. Bharat?s work was supported by an Australian National Health and Medical Research Council (NHMRC) grant (no. 1081984). The authors thank the WMH Coordinating Center staff at Harvard and Michigan Universities for their assistance with the instrumentation, fieldwork and data analysis. These activities were supported by the United States National Institute of Mental Health (R01MH070884), the John D. and Catherine T. MacArthur Foundation, the Pfizer Foundation, the U.S. Public Health Service (R13-MH066849, R01-MH069864, and R01 DA016558), the Fogarty International Center (FIRCA R03-TW006481), the Pan American Health Organization, the Eli Lilly & Company Foundation, Ortho-McNeil Phar-maceutical, Inc., GlaxoSmithKline, Bristol-Myers Squibb and Shire. A complete list of WMH publications can be found at http://www.hcp.med.harvard.edu/wmh/. The direct and indirect founders had no role in study design, data collection and analysis, decision to publish, or prepa-ration of the manuscript.

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Bibliographic References

  • Abdin, E., Subramaniam, M., Vaingankar, J. A. & Chong, S. A. (2013). The role of sociodemographic factors in the risk of transition from alcohol use to disorders and remission in singapore. Alcohol and Alcoholism, 49, 103-108. doi:10.1093/alcalc/agt126.
  • Alonso, J., Angermeyer, M. C., Bernert, S., Bruffaerts, R., Brugha, T. S., Bryson, H.,… Vollebergh, W. (2004). Prevalence of mental disorders in europe: Results from the European Study of the Epidemiology of Mental Disorders (ESEMeD) project. Acta Psychiatrica Scandinavica, 109, 21-27. doi:10.1111/j.1600-0047.2004.00327.x.
  • American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders (Fourth edition - Text revision). Washington, DC: American Psychiatric Association.
  • Blanco, C., Okuda, M., Wright, C., Hasin, D. S., Grant, B. F., Liu, S.-M. & Olfson, M. (2008). Mental health of college students and their non–college-attending peers: Results from the national epidemiologic study on alcohol and related conditions. Archives of General Psychiatry, 65, 1429-1437. doi:10.1001/archpsyc.65.12.1429.
  • Carballo, J. L., Fernandez-Hermida, J. R., Secades-Villa, R. & García-Rodríguez, O. (2008). Determinants of recovery from alcohol problems in treated and untreated individuals in a spanish sample. Adicciones, 20, 49-58.
  • Carballo, J. L., Fernández-Hermida, J. R., Sobell, L. C., Dum, M., Secades-Villa, R., García-Rodríguez, O.,… AlHalabí-Diaz, S. (2008). Differences among substance abusers in spain who recovered with treatment or on their own. Addictive Behaviors, 33, 94-105. doi:10.1016/j.addbeh.2007.07.013.
  • Cheng, H. G., Chandra, M., Alcover, K. C. & Anthony, J. C. (2016). Rapid transition from drinking to alcohol dependence among adolescent and young-adult newly incident drinkers in the united states, 2002–2013. Drug & Alcohol Dependence, 168, 61-68. doi:10.1016/j.drugalcdep.2016.08.015.
  • Conway, K. P., Swendsen, J., Husky, M. M., He, J.P. & Merikangas, K. R. (2016). Association of lifetime mental disorders and subsequent alcohol and illicit drug use: Results from the national comorbidity survey–adolescent supplement. Journal of the American Academy of Child & Adolescent Psychiatry, 55, 280-288. doi:10.1016/j.jaac.2016.01.006.
  • Degenhardt, L., Chiu, W.-T., Sampson, N., Kessler, R. C., Anthony, J. C., Angermeyer, M.,… Huang, Y. (2008). Toward a global view of alcohol, tobacco, cannabis, and cocaine use: Findings from the WHO World Mental Health surveys. PLoS Medicine, 5, e141. doi:10.1371/journal.pmed.0050141.
  • Degenhardt, L., Stockings, E., Patton, G., Hall, W. D. & Lynskey, M. (2016). The increasing global health priority of substance use in young people. Lancet Psychiatry, 3, 251-264. doi:10.1016/S2215-0366(15)00508-8.
  • Demyttenaere, K., Bruffaerts, R., Posada-Villa, J., Gasquet, I., Kovess, V., Lepine, J. P., . . . WHO World Mental Health Survey Consortium. (2004). Prevalence, severity, and unmet need for treatment of mental disorders in the World Health Organization World Mental Health surveys. Journal of the American Medical Association, 291, 2581-2590. doi:10.1001/jama.291.21.2581.
  • DeWit, D. J., Adlaf, E. M., Offord, D. R. & Ogborne, A. C. (2000). Age at first alcohol use: A risk factor for the development of alcohol disorders. American Journal of Psychiatry, 157, 745-750. doi:10.1176/appi.ajp.157.5.745.
  • Flórez-Salamanca, L., Secades-Villa, R., Hasin, D. S., Cottler, L., Wang, S., Grant, B. F. & Blanco, C. (2013). Probability and predictors of transition from abuse to dependence on alcohol, cannabis, and cocaine: Results from the national epidemiologic survey on alcohol and related conditions. The American Journal of Drug and Alcohol Abuse, 39, 168-179. doi:10.3109/00952990.2013.772618.
  • Grant, B. F. (1997). Prevalence and correlates of alcohol use and DSM-IV alcohol dependence in the United States: Results of the national longitudinal alcohol epidemiologic survey. Journal of Studies on Alcohol, 58, 464-473. doi:10.15288/jsa.1997.58.464.
  • Grant, B. F., Stinson, F. S. & Harford, T. C. (2001). Age at onset of alcohol use and DSM-IV alcohol abuse and dependence: A 12-year follow-up. Journal of Substance Abuse, 13, 493-504. doi:10.1016/S0899-3289(01)00096-7.
  • Gual, A., Arbesú, J. Á., Zarco, J., López-Pelayo, H., Miquel, L. & Bobes, J. (2016). Alcoholism and its treatment approach from a citizen perspective. Adicciones, 28. 163-173. doi:10.20882/adicciones.742.
  • Johnson, E. O. & Schultz, L. (2005). Forward telescoping bias in reported age of onset: An example from cigarette smoking. International Journal of Methods in Psychiatric Research, 14, 119-129. doi:10.1002/mpr.2.
  • Kalaydjian, A., Swendsen, J., Chiu, W.-T., Dierker, L., Degenhardt, L., Glantz, M.,… Kessler, R.C. (2009). Sociodemographic predictors of transitions across stages of alcohol use, disorders and remission in the national comorbidity survey-replication. Comprehensive Psychiatry, 50, 299-306. doi:10.1016/j.comppsych.2008.09.012.
  • Kessler, R.C. & Ustun, T. B. (2004). The World Mental Health (WMH) survey initiative version of the World Health Organization (WHO) Compositve International Diagnostic Interview (CIDI). International Journal of Methods in Psychiatric Research, 13, 93-121. doi:10.1002/mpr.168.
  • Knäuper, B., Cannell, C. F., Schwarz, N., Bruce, M. L. & Kessler, R. C. (1999). Improving accuracy of major depression age-of-onset reports in the U.S. National Comorbidity Survey. International Journal of Methods in Psychiatric Research, 8, 39-48. doi:10.1002/mpr.55.
  • Kovess-Masfety, V., Leray, E., Denis, L., Husky, M., Pitrou, I. & Bodeau-Livinec, F. (2016). Mental health of college students and their non-college-attending peers: Results from a large french cross-sectional survey. BMC Psychology, 4. doi:10.1186/s40359-016-0124-5.
  • Lee, S., Guo, W. J., Tsang, A., He, Y. L., Huang, Y. Q., Zhang, M. Y.,… Kessler, R. C. (2009). Associations of cohort and socio-demographic correlates with transitions from alcohol use to disorders and remission in metropolitan China. Addiction, 104, 1313-1323. doi:10.1111/j.1360-0443.2009.02595.x.
  • Lev-Ran, S., Imtiaz, S., Rehm, J. & Le Foll, B. (2013). Exploring the association between lifetime prevalence of mental illness and transition from substance use to substance use disorders: Results from the National Epidemiologic Survey of Alcohol and Related Conditions (NESARC). The American Journal on Addictions, 22, 93-98. doi:10.1111/j.1521-0391.2013.00304.x.
  • Lopez-Quintero, C., Cobos, J. P., Hasin, D. S., Okuda, M., Wang, S., Grant, B. F. & Blanco, C. (2011). Probability and predictors of transition from first use to dependence on nicotine, alcohol, cannabis, and cocaine: Results of the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC). Drug and Alcohol Dependence, 115, 120-130. doi:10.1016/j.drugalcdep.2010.11.004.
  • Mateos, R., Páramo, M., Carrera, I. & Rodríguez-López, A. (2002). Alcohol consumption in a southern european region (Galicia, Spain). Substance Use & Misuse, 37, 1957-1976. doi:10.1081/JA-120016226.
  • Navarro-Mateu, F., Tormo, M., Vilagut, G., Alonso, J., Ruiz-Merino, G., Escamez, T.,… Navarro, C. (2013a). Epidemiology and genetics of common mental disorders in the general population: The PEGASUS-Murcia project. BMJ Open, 3. doi:10.1136/bmjopen-2013-004035.
  • Navarro-Mateu, F., Morán-Sánchez, I., Alonso, J., Tormo, M. J., Pujalte, M. L., Garriga, A.,… Navarro, C. (2013b). Cultural adaptation of the latin american version of the World Health Organization Composite International Diagnostic Interview (CIDI v 3.0) for use in Spain. Gaceta Sanitaria, 27, 325-331. doi:10.1016/j.gaceta.2012.06.005.
  • Navarro-Mateu, F., Tormo, M. J., Salmerón, D., Vilagut, G., Navarro, C., Ruíz-Merino, G.,… Kessler, R. C. (2015). Prevalence of mental disorders in the south-east of spain, one of the european regions most affected by the economic crisis: The cross-sectional pegasus-murcia project. PLoS One, 10. doi:10.1371/journal.pone.0137293.
  • Oberleitner, L. M., Smith, P. H., Weinberger, A. H., Mazure, C. M. & McKee, S. A. (2015). Impact of exposure to childhood maltreatment on transitions to alcohol dependence in women and men. Child Maltreatment, 20, 301-308. doi:10.1177/1077559515591270.
  • Observatorio Español de la Droga y las Toxicomanías. (2017). Edades 2015-2016. Encuesta sobre alcohol y drogas en españa. Madrid: Delegación del gobierno para el plan nacional sobre drogas. Retrieved at http://www.pnsd.msssi.gob.es/profesionales/sistemasInformacion/sistemaInformacion/pdf/2015_EDADES__Informe_.pdf.
  • Paschall, M. J., Grube, J. W. & Kypri, K. (2009). Alcohol control policies and alcohol consumption by youth: A multi-national study. Addiction, 104, 1849-1855. doi:10.1111/j.1360-0443.2009.02698.x.
  • Pérez, B. (2002). El alcohol como problema de salud pública. La responsabilidad de los poderes públicos. Adicciones, 14, 291-301.
  • Pollard, J. W., Freeman, J. E., Ziegler, D. A., Hersman, M. N. & Goss, C. W. (2000). Predictions of normative drug use by college students. Journal of College Student Psychotherapy, 14, 5-12. doi:10.1300/J035v14n03_03.
  • Probst, C., Moyo, D., Purshouse, R. & Rehm, J. (2015). Transition probabilities for four states of alcohol use in adolescence and young adulthood: What factors matter when? Addiction, 110, 1272-1280. doi:10.1111/add.12985.
  • Rehm, J., Anderson, P., Barry, J., Dimitrov, P., Elekes, Z., Feijão, F.,… Kraus, L. (2015). Prevalence of and potential influencing factors for alcohol dependence in Europe. European Addiction Research, 21, 6-18. doi:10.1159/000365284.
  • Rehm, J., Gmel, G. & Gual, A. (2013). Alcohol consumption, alcohol dependence and related harms in Spain, and the effect of treatment-based interventions on alcohol dependence. Adicciones, 25, 11-18.
  • Rehm, J., Mathers, C., Popova, S., Thavorncharoensap, M., Teerawattananon, Y. & Patra, J. (2009). Global burden of disease and injury and economic cost attributable to alcohol use and alcohol-use disorders. The Lancet, 373, 2223-2233. doi:10.1016/S0140-6736(09)60746-7.
  • Robledo de Dios, T. (2002). Políticas institucionales de prevención de los problemas de salud generados por el consumo de bebidas alcohólicas en España y Europa. Adicciones, 14, S303-S315.
  • Shillington, A. M., Woodruff, S. I., Clapp, J. D., Reed, M. B. & Lemus, H. (2012). Self-reported age of onset and telescoping for cigarettes, alcohol, and marijuana: Across eight years of the national longitudinal survey of youth. Journal of Child & Adolescent Substance Abuse, 21, 333-348. doi:10.1080/1067828X.2012.710026.
  • Silveira, C. M., Viana, M. C., Siu, E. R., de Andrade, A. G., Anthony, J. C. & Andrade, L. H. (2011). Sociodemographic correlates of transitions from alcohol use to disorders and remission in the Sao Paulo megacity mental health survey, brazil. Alcohol and Alcoholism, 46, 324-332. doi:10.1093/alcalc/agr007.
  • Slade, T., Chapman, C., Swift, W., Keyes, K., Tonks, Z. & Teesson, M. (2016). Birth cohort trends in the global epidemiology of alcohol use and alcohol-related harms in men and women: Systematic review and metaregression. BMJ Open, 6. doi:10.1136/bmjopen-2016-011827.
  • Suliman, S., Seedat, S., Williams, D. R. & Stein, D. J. (2010). Predictors of transitions across stages of alcohol use and alcohol-use disorders in South Africa. Journal of Studies on Alcohol and Drugs, 71, 695-703. doi:10.15288/jsad.2010.71.695.
  • von Elm, E., Altman, D.G., Egger, M., Pocock, S.J., Gotzsche, P.C. & Vandenbroucke, J.P. (2007). The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies. PLoS Med, 4: e296. doi:10.1371/journal.pmed.0040296.
  • Werner, K. B., Sartor, C. E., McCutcheon, V. V., Grant, J. D., Nelson, E. C., Heath, A. C. & Bucholz, K. K. (2016). Association of specific traumatic experiences with alcohol initiation and transitions to problem use in european american and african american women. Alcoholism: Clinical and Experimental Research, 40, 2401-2408. doi:10.1111/acer.13220.
  • World Health Organization. (2014). Global status report on alcohol and health. Geneva, Switzerland: World Health Organization.
Data source: Dialnet