Cognitive flexibility and response inhibition in patients with Obsessive-Compulsive Disorder and Generalized Anxiety Disorder

  1. Ángel Rosa-Alcázar 1
  2. Pablo J. Olivares-Olivare 2
  3. Inmaculada Concepción Martínez-Esparza 2
  4. José Luis Parada-Navas 2
  5. Ana I. Rosa-Alcázar 2
  6. José Olivares-Rodríguez 2
  1. 1 Universidad Católica San Antonio
    info

    Universidad Católica San Antonio

    Murcia, España

    ROR https://ror.org/05b1rsv17

  2. 2 Universidad de Murcia
    info

    Universidad de Murcia

    Murcia, España

    ROR https://ror.org/03p3aeb86

Revista:
International journal of clinical and health psychology

ISSN: 1697-2600

Año de publicación: 2020

Volumen: 20

Número: 1

Páginas: 20-28

Tipo: Artículo

DOI: 10.1016/J.IJCHP.2019.07.006 DIALNET GOOGLE SCHOLAR lock_openAcceso abierto editor

Otras publicaciones en: International journal of clinical and health psychology

Resumen

Antecedentes/Objetivo El objetivo de este estudio fue analizar las diferencias en flexibilidad cognitiva e inhibición de respuestas teniendo en cuenta algunas variables que pueden influir en los resultados (razonamiento no verbal, depresión, ansiedad, intolerancia a la incertidumbre, comorbilidad, consumo de fármacos). Método Los participantes fueron 95 adultos de edades comprendidas entre 17-61 años (M=33,48; DT=11,13), diagnosticados de Trastorno obsesivo-compulsivo, Trastorno de ansiedad generalizada y un grupo de control sano. Las variables neuropsicológicas fueron evaluadas con el Test de Clasificación de Tarjetas de Wisconsin, Test Stroop de Colores y Palabras y Tareas Go/NoGo. Resultados Los grupos clínicos presentaron peores resultados en flexibilidad cognitiva frente al grupo control. El grupo obsesivo-compulsivo alcanzó peores puntuaciones en flexibilidad que el grupo con ansiedad generalizada, una vez controlado el razonamiento no verbal y la tolerancia a la incertidumbre. La comorbilidad y el consumo de fármacos no afectaron a los resultados en el grupo obsesivo-compulsivo. Sin embargo, ambas variables influyeron en el grupo con ansiedad generalizada. Conclusiones La flexibilidad cognitiva podría ser incluida en los paquetes de tratamiento del Trastorno obsesivo-compulsivo y del Trastorno de ansiedad generalizada.

Información de financiación

Referencias bibliográficas

  • Abramovitch, A., Abramowitz, J. S., & Mittelman, A. (2013). The neuropsychology of adult obsessive---compulsive disorder: A meta-analysis. Clinical Psychology Review, 33, 1163---1171. http://dx.doi.org/10.1016/j.cpr.2013.09.004
  • Abramovitch, A., Dar, R., Hermesh, H., & Schweiger, A. (2012). Comparative neuropsychology of adult obsessive-compulsive disorder and attention deficit/hyperactivity disorder: Implications for a novel executive overload model of OCD. Journal of Neuropsychology, 6, 161---191. http://dx.doi.org/ 10.1111/j.1748-6653.2011.02021.x
  • Abramovitch, A., Dar, R., Schweiger, A., & Hermesh, H. (2011). Neuropsychological impairments and their association with obsessive-compulsive symptom severity in obsessive-compulsive disorder. Archives of Clinical Neuropsychology, 26, 364---376. http://dx.doi.org/10.1093/arclin/acr022
  • Abramovitch, A., McCormack, B., Brunner, D., Johnson, M., & Wofford, N. (2018). The impact of symptom severity on cognitive function in obsessive-compulsive disorder: A meta-analysis. Clinical Psychology Review, 67, 3---44. http://dx.doi.org/10.1016/j.cpr.2018.09.003
  • American Psychiatric Association APA. (2013). Diagnostic and statistical manual of mental disorders, DSM-5. Arlington: American Psychiatric Publishing.
  • Beck, A. T., & Steer, R. A. (1996). Inventario de Ansiedad de Beck (BAI). Madrid: Pearson.
  • Beck, A. T., Steer, R. A., Brown, G. K., Sanz, J., & Valverde, C. V. (2011). Inventario de depresión de Beck (BDI-II). Madrid: Pearson. Carlson, S. M., & Wang, T. S. (2007). Inhibitory control and emotion regulation in preschool children. Cognitive Development, 22, 489---510. http://dx.doi.org/10.1016/j.cogdev.2007.08.002
  • Carver, C. S., Johnson, S. L., & Timpano, K. R. (2017). Toward a functional view of the p factor in psychopathology. Clinical Psychological Science, 5, 880---889. http://dx.doi.org/10.1177/2167702617710037
  • Diamond, A. (2013). Executive functions. Annual Review of Psychology, 64, 135. http://dx.doi.org/10.1146/annurev-psych-113011-143750
  • Dittrich, W. H., & Johansen, T. (2013). Cognitive deficits of executive functions and decision-making in obsessive-compulsive disorder. Scandinavian Journal of Psychology, 54, 393---400. http://dx.doi.org/10.1111/sjop.12066
  • Dugas, M. J., Gagnon, F., Ladouceur, R., & Freeston, M. H. (1998). Generalized anxiety disorder: A preliminary test of a conceptual model. Behaviour Research and Therapy, 36, 215---226. http://dx.doi.org/10.1016/S0005-7967(97)00070-3
  • Freeston, M. H., Rhéaume, J., Letarte, H., Dugas, M. J., & Ladouceur, R. (1994). Why do people worry? Personality and Individual Differences, 17, 791---802. http://dx.doi.org/10.1016/0191-8869(94)90048-5
  • Geller, D. A., Abramovitch, A., Mittelman, A., Stark, A., Ramsey, K., Cooperman, A., Baer, L., & Stewart, S. E. (2018). Neurocognitive function in pediatric obsessive-compulsive disorder. The World Journal of Biological Psychiatry, 19, 142---151. http://dx.doi.org/10.1080/15622975.2017.1282173
  • Golden, C. J. (1999). Stroop: Test de colores y palabras. Madrid: TEA.
  • Goodman, W. K., Price, L. H., Rasmussen, S. A., Mazure, C., Fleischmann, R. L., Hill, C. L., Henninge, G. R., & Charney, D. S. (1989). The Yale-Brown obsessive compulsive scale: I. Development, use, and reliability. Archives of General Psychiatry, 46, 1006---1011. http://dx.doi.org/10.1001/archpsyc.1989.01810110048007
  • Hallion, L. S., Tolin, D. F., Assaf, M., Goethe, J., & Diefenbach, G. J. (2017). Cognitive Control in Generalized Anxiety Disorder: Relation of Inhibition Impairments to Worry and Anxiety Severity. Cognitive Therapy and Research, 4, 610---618. http://dx.doi.org/10.1007/s10608-017-9832-2
  • Heaton, R. K., Chelune, G. J., Talley, J. L., Kay, G. G., & Curtiss, G. (2001). WCST: Test de clasificación de tarjetas de Wisconsin. Madrid: TEA.
  • Kim, K. L., Christensen, R. E., Ruggieri, A., Schettini, E., Freeman, J. B., Garcia, A. M., Flessner, C., Stewart, E., Conelea, C., & Dickstein, D. P. (2019). Cognitive performance of youth with primary generalized anxiety disorder versus primary obsessive---compulsive disorder. Depression and Anxiety, 36, 130---140. http://dx.doi.org/10.1002/da.22848
  • Kurt, E., Yildirim, E., & Topc¸uo˘glu, V. (2017). Executive Functions of Obsessive Compulsive Disorder and Panic Disorder Patients in Comparison to Healthy Controls. Archives of Neuropsychiatry, 54, 312. http://dx.doi.org/10.5152/npa.2016.14872
  • Laposa, J. M., Collimore, K. C., Hawley, L. L., & Rector, N. A. (2015). Distress tolerance in OCD and anxiety disorders, and its relationship with anxiety sensitivity and intolerance of uncertainty. Journal of Anxiety Disorders, 33, 8---14. http://dx.doi.org/10.1016/j.janxdis.2015.04.003
  • Leonard, K., & Abramovitch, A. (2018). Cognitive functions in young adults with generalized anxiety disorder. European Psychiatry, 56, 1---7. http://dx.doi.org/10.1016/j.eurpsy.2018.10.008
  • Meyer, T. J., Miller, M. L., Metzger, R. L., & Borkovec, T. D. (1990). Development and validation of the penn state worry questionnaire. Behaviour Research and Therapy, 28, 487---495. http://dx.doi.org/10.1016/0005-7967(90)90135-6
  • Miyake, A., & Friedman, N. P. (2012). The nature and organization of individual differences in executive functions four general conclusions. Current Directions in Psychological Science, 21, 8---14.
  • Moritz, S., Birkner, C., Kloss, M., Jahn, H., Hand, I., Haasen, C., & Krausz, M. (2002). Executive functioning in obsessive---compulsive disorder, unipolar depression, and schizophrenia. Archives of Clinical Neuropsychology, 17, 477---483. http://dx.doi.org/10.1016/S0887-6177(01)00130-5
  • Park, J., & Moghaddam, B. (2017). Impact of anxiety on prefrontal cortex encoding of cognitive flexibility. Neuroscience, 345, 193---202. http://dx.doi.org/10.1016/j.neuroscience.2016.06.013
  • Pascual-Vera, B., Akin, B., Belloch, A., Bottesi, G., Clark, D. A., Doron, G., Fernández-Álvarez, H., Ghisi, M., Gómez, B., Inozu, M., Jiménez-Ros, A., Moulding, R., Ruiz, M. A., & Jiménez-Ros, A. (2019). The cross-cultural and transdiagnostic nature of unwanted mental intrusions. International Journal of Clinical and Health Psychology, 19, 85---96. http://dx.doi.org/10.1016/j.ijchp.2019.02.005
  • Peris, T. S., Rozenman, M., Bergman, R. L., Chang, S., O’Neill, J., & Piacentini, J. (2017). Developmental and clinical predictors of comorbidity for youth with obsessive compulsive disorder. Journal of Psychiatric Research, 93, 72---78. http://dx.doi.org/10.1016/j.jpsychires.2017.05.002
  • Reynolds, C. R., Kamphaus, R. W., Fernández, P. S., & Pinto, I. F. (2009). RIAS: escalas de inteligencia de Reynolds y; RIST: test de inteligencia breve de Reynolds. Madrid: TEA.
  • Rosa-Alcázar, Á., Rosa-Alcázar, A. I., Olivares-Olivares, P. J., Parada-Navas, J. L., Rosa-Alcázar, E., & Sánchez-Meca, J. (2019). Family involvement and treatment for young children with Obsessive-Compulsive Disorder: Randomized control study. International Journal of Clinical and Health Psychology., http://dx.doi.org/10.1016/j.ijchp.2019.06.001
  • Shin, N. Y., Lee, T. Y., Kim, E., & Kwon, J. S. (2014). Cognitive functioning in obsessive-compulsive disorder: A meta-analysis. Psychological Medicine, 44, 1121---1130. http://dx.doi.org/10.1017/S0033291713001803
  • Snyder, H. R., Kaiser, R. H., Warren, S. L., & Heller, W. (2015). Obsessive-compulsive disorder is associated with broad impairments in executive function: A metaanalysis. Clinical Psychological Science, 3, 301---330. http://dx.doi.org/10.1177/2167702614534210
  • Taboas, W., Ojserkis, R., & McKay, D. (2015). Change in disgust reactions following cognitive-behavioral therapy for childhood anxiety disorders. International Journal of Clinical and Health Psychology, 15, 1---7. http://dx.doi.org/10.1016/j.ijchp.2014.06.002
  • Teubner-Rhodes, S., Vaden, K. I., Jr., Dubno, J. R., & Eckert, M. A. (2017). Cognitive persistence: Development and validation of a novel measure from the Wisconsin Card Sorting Test. Neuropsychologia, 102, 95---108. http://dx.doi.org/10.1016/j.neuropsychologia.2017.05.027
  • Wersebe, H., Lieb, R., Meyer, A. H., Miche, M., Mikoteit, T., Imboden, C., Bader, K., Hatzinger, M., & Gloster, A. T. (2018). Well-being in major depression and social phobia with and without comorbidity. International Journal of Clinical and Health Psychology, 18, 201---208. http://dx.doi.org/10.1016/j.ijchp.2018.06.004
  • Yazdi-Ravandi, S., Shamsaei, F., Matinnia, N., Moghimbeigi, A., Shams, J., Ahmadpanah, M., & Ghaleiha, A. (2018). Executive functions, selective attention and information processing in patients with obsessive compulsive disorder: A study from west of Iran. Asian Journal of Psychiatry, 37, 140---145. http://dx.doi.org/10.1016/j.ajp.2018.09.002