Terapia con células madre en medicina veterinaria:conceptos generales y evidencias clínicas
- J. Talavera 1
- J.I. Gil-Chinchilla 1
- D. García 1
- G. Castellanos 1
- M.D. López Lucas 1
- N.M. Atucha 1
- J.M. Moraleda 1
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1
Universidad de Murcia
info
ISSN: 1130-7064
Year of publication: 2017
Volume: 37
Issue: 2
Pages: 87-101
Type: Article
More publications in: Clínica veterinaria de pequeños animales: revista oficial de AVEPA, Asociación Veterinaria Española de Especialistas en Pequeños Animales
Abstract
Stem cells are undifferentiated cells with self-renewal and differentiation properties that give rise to cells of different lineages. Mesenchymal stem cells are present in the stroma of different adult and extraembryonic tissues and are involved in cell regeneration and in the modulation of biochemical signals involved in the continuous repair of tissues and organs. The identification of stem cells gives great hopes for the treatment of many diseases where conventional therapies are unsuccessful. This manuscript reviews the current knowledge derived from scientific studies with a direct impact on the veterinary medical diseases. Thus, the aim is to provide the veterinary clinician interested in such therapies with basic information to decide whether to offer their patients this therapeutic option. In addition to exposing basic aspects of the biology of stem cells, existing scientific evidence derived from clinical studies in veterinary patients, the basics about the current regulation for such therapies and the current intervention of scientific agents in the establishment of standards of treatment are also discussed.