Estudio comparativo de diversos métodos de inducción de aterogénesis experimental en el pollo

1. Ayala de la Peña, Ignacio
2. García Pérez, Bartolomé
3. Doménech Asensi, Guillermo
4. Sánchez Polo, María Teresa
5. Ortega, J.V.
6. Castells Mora, María Teresa

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More publications in: Anales de veterinaria de Murcia

Abstract

Atherosclerosis and its consequences continue to be the major cause of death in Europe and the United Status. Animals have been used as experimental models in atherosclerosis-related research since the turn of the past century. The chicken is a good animal model and offers economic and technical advantages over mammalian models. Furthermore, it is able to develop spontaneous and induced atherosclerosis, and there is no essential difference between vascular lesions seen in chickens as a result of cholesterol diet and that of atherosclerosis observed in man. In this work, we examine several induction methods of atherogenesis in the chicken experimental model. It may be concluded that adding cholesterol to an standard diet gives better results, than using an egg-based diet. Palm oil results an excellent mean of increasing the digestive absortion of cholesterol. The atherogenic diet must be administered ad libitum.

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