Pericytes for use as a medicament

  1. Inventors:
  2. Rut Valdor Alonso
  3. David Garcia Bernal
  4. Jose Maria Moraleda Jimenez
  5. Salvador Martinez Perez
  1. Universidad de Murcia
    info
    Universidad de Murcia

    Murcia, España

    Geographic location of the organization Universidad de Murcia
WO EP US
Publicación principal:

EP4202038A1 (28-06-2023)

Otras Publicaciones:

EP4453185A1 (30-10-2024)

EP4202038A1 (28-06-2023)

WO2023117805A1 (29-06-2023)

US20250057889A1 (20-02-2025)

Abstract

The present invention refers to a substantially pure population of pericytes, or cell suspension comprising pericytes, wherein the pericytes are at least 80% of the total cell population or suspension, characterized in that CMA is inhibited, for example by inhibiting the expression or deleting the gene LAMP2A. In a preferred embodiment, said population or suspension of pericytes is used as a medicament, for instance in the treatment of cancer, preferably glioblastoma.

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