Maria Concepcion
Olivares Sanchez
Profesores Titulares de Universidad
Jose Carlos
Garcia-Borron Martinez
Catedraticos de Universidad
2025
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An MGRN1-Based Biomarker Combination Accurately Predicts Melanoma Patient Survival
International Journal of Molecular Sciences, Vol. 26, Núm. 4, pp. 1739
2024
2023
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A Side-by-Side Comparison of Wildtype and Variant Melanocortin 1 Receptor Signaling with Emphasis on Protection against Oxidative Damage to DNA
International Journal of Molecular Sciences, Vol. 24, Núm. 18
2022
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MGRN1 as a Phenotypic Determinant of Human Melanoma Cells and a Potential Biomarker
Life, Vol. 12, Núm. 8
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Mahogunin Ring Finger 1 regulates pigmentation by controlling the pH of melanosomes in melanocytes and melanoma cells
Cellular and Molecular Life Sciences, Vol. 79, Núm. 1
2020
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Functional characterization of a C-terminal splice variant of the human melanocortin 1 receptor
Experimental Dermatology, Vol. 29, Núm. 7, pp. 610-615
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Mahogunin ring finger 1 is required for genomic stability and modulates the malignant phenotype of melanoma cells
Cancers, Vol. 12, Núm. 10, pp. 1-23
2019
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Actions of variant melanocortin 1 receptor: akt-mediated activation of protective responses to oxidative DNA damage
IV Jornadas Doctorales Escuela Internacional de Doctorado de la Universidad de Murcia (Eidum)
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Inestabilidad genómica y progresión aberrante del ciclo celular en melanocitos Mgrn1-Ko
IV Jornadas Doctorales Escuela Internacional de Doctorado de la Universidad de Murcia (Eidum)
2018
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CAMP-independent non-pigmentary actions of variant melanocortin 1 receptor: AKT-mediated activation of protective responses to oxidative DNA damage
Oncogene, Vol. 37, Núm. 27, pp. 3631-3646
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Conjugation with dihydrolipoic acid imparts caffeic acid ester potent inhibitory effect on dopa oxidase activity of human tyrosinase
International Journal of Molecular Sciences, Vol. 19, Núm. 8
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Human melanocortin 1 receptor-mediated ubiquitination of nonvisual arrestins. Role of Mahogunin Ring Finger 1 E3 ligase
Biochimica et Biophysica Acta - Molecular Cell Research, Vol. 1865, Núm. 1, pp. 76-94
2017
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MC1R signaling. Intracellular partners and pathophysiological implications
Biochimica et Biophysica Acta - Molecular Basis of Disease, Vol. 1863, Núm. 10, pp. 2448-2461
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Mahogunin RING Finger 1 regulates pigmentation by modulation of the melanosomal pH J
III Jornadas Doctorales Escuela Internacional de Doctorado de la Universidad de Murcia (EIDUM)
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Mgrn1: proteína reguladora de la proliferación y diferenciación de los melanocitos
III Jornadas Doctorales Escuela Internacional de Doctorado de la Universidad de Murcia (EIDUM)
2015
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Functional characterization of MC1R-TUBB3 intergenic splice variants of the human melanocortin 1 receptor
PLoS ONE, Vol. 10, Núm. 12
2014
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Melanocortin 1 receptor and skin pathophysiology: Beyond colour, much more than meets the eye
Experimental Dermatology, Vol. 23, Núm. 6, pp. 387-388
2013
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Differential and competitive regulation of human melanocortin 1 receptor signaling by β-arrestin isoforms
Journal of Cell Science, Vol. 126, Núm. 16, pp. 3724-3737
2011
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Biosynthesis of Melanins
Melanins and Melanosomes: Biosynthesis, Biogenesis, Physiological, and Pathological Functions (Wiley-VCH), pp. 87-116
2009
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Mahogunin ring finger-1 (MGRN1) E3 ubiquitin ligase inhibits signaling from melanocortin receptor by competition with Gαs
Journal of Biological Chemistry, Vol. 284, Núm. 46, pp. 31714-31725