Farmacocinética intravenosa y unión a proteínas plasmáticas de amoxicilina y ácido clavulánico en ovinos

  1. Serrano, J.M.
  2. Hita, J.
  3. Ponferrada, C.J.
  4. López, M.C.
  5. Carlos Mario Cárceles Rodríguez 1
  1. 1 Universidad de Murcia
    info

    Universidad de Murcia

    Murcia, España

    ROR https://ror.org/03p3aeb86

Journal:
Anales de veterinaria de Murcia

ISSN: 0213-5434,  1989-1784

Year of publication: 1989

Issue: 5

Pages: 75-87

Type: Article

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Abstract

A kinetic survey of arnoxycillin and clavulanic acid after intravenous admiiiistration in sheep has beeii studied. After the corresponding pharmacokiiietics studies results show a better adjustmeni to bicompartinieiital niodels which numerical expressions are respectively as follows: ct = 225.40 e 1-Il.14h2 1) + 98.97 e [.U.fXW? . 11 m f l Clavulanic acid: Ct = 97.27 e [4'.1%3 '1) + 34 42 e (.O.MPW ' I l nld The amoxycillin and clavulanic acid binding to plasma proteins have shown an average union percentage of 16.33% and 17.07% respectively.

Data source: Dialnet